Evidence-based nutrition, in plain English — every entry sourced from clinical research.

EPA and DHA are the two long-chain omega-3 fats found in oily fish — the active forms the body uses most readily, unlike the plant omega-3 (ALA) it converts only slowly. DHA is a structural building block of the brain and retina, while both EPA and DHA help calm inflammation and support the heart. They are also what the omega-3 index measures: the proportion of these fats in your red blood cells, a marker that rises directly with how much oily fish you eat.

What is EPA & DHA?

EPA & DHA is a marine omega-3 fat that plays a critical role in building the brain and retina and helping regulate inflammation and a steady heart rhythm. While many general diets overlook it, maintaining optimal levels of EPA & DHA is frequently tracked by people working to optimize their Omega-3 Index.

Top Foods High in EPA & DHA

A data-driven breakdown of the foods with the highest concentration of EPA & DHA per 100 g.

Highest dietary sources of EPA & DHA, per 100 g edible portion
FoodEPA & DHA
Mackerel2.3 g
Sardines0.98 g
Salmon (Atlantic)0.9 g
Rainbow Trout0.73 g
Mussels0.44 g
Tuna (canned, light)0.22 g
Cod0.18 g
Scallops0.1 g
Eggs0.06 g

How EPA & DHA Impacts Omega-3 Index

Research links diets rich in EPA & DHA to changes in Omega-3 Index. Optimizing intake of these foods can support healthy Omega-3 Index levels via being incorporated directly into red-blood-cell membranes — which is exactly what the omega-3 index measures.

Encyclopedia Insight: For maximum absorption, pair EPA & DHA-rich foods with a regular habit of oily fish a couple of times a week, since the index reflects long-term intake, not a single meal to optimize bioavailability.

Written by the Nutrition Encyclopedia team · medically reviewed by Dr. Sunaina Tariq, MBBS

Last updated 22 June 2026

Nutrition values are approximations compiled from public food-composition databases (USDA FoodData Central) and are provided for educational purposes only — not medical advice.

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